I have a 1995 Ford Ranger with a 3.0 V6 and an automatic overdrive transmission, it starts and idles fine. When driving it runs great until it shifts into drive or overdrive, and then it vibrates a little bit and then it stalls like it runs out of fuel and when I let off the throttle it picks right back up. I have changed fuel filter, plugs, even changed the ECM and still does the same thing, please help

change the oil and run the fault codes
take it to an accredited professional transmission specialist for a proper diagnosis

Slipping O/D sprag

You need to run a fault code test on the automatic transmission. Go here to see how to do that.

Make sure the fulid is at the safe level in the tranny when it is warm, I have the fluid dosent smell burnt, if both things are fine then your transmission might be sliping indeed.

Trans fluid level and condition, also the filter even though the filter is metal can be clean from the back to the front with compress air.

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NO. Too little could. Does it still drive and shift at all?

I have a 91 ranger. There are two band adjustments on the transmission that is supposed to be adjusted every 60K miles. There are two adjustments, one for overdrive and the other for everything else. The overdrive adjustment is closest to the front of the transmission and the other is back behind it closer to the shift lever on the driver side. The locking nut is a 19" and there is a tool you get for the other nut. I have found a 3/8th (I believe) 12 point socket will fit on the square. You loosen the lock nut, then you tighten the band adjustment bolt to 10 foot pounds. Then you back the bolt off 2 full turns, then hold it in place while re-tightening your lock nut. I had to adjust my bolt in 1/4 turns at a time after test driving to get the transmission to shift just right.

your transmission is slipping

I had to replace the air by pass valve when my 1987 ford ranger supercab was doing that... good luck

Sounds like the shift kit is warn out in the transmission. The overdrive line may not be able to provide enough hydrolic pressure to engage the gears to move the truck. When you switch to regualr drive, that line is able to build the hydrolic pressure to engage the gears. At a certian speed (for the transmission, certian hydrolic pressure) there is enough pressure to engage the gears in overdrive, but go below that, and you have to start in drive again. If this is the case, there is no easy fix for that and I recomend taking it to a transmission shop to have your shift kit examined. Opening up an automatic transmission requires specalized tools, clean shop enviroment, and knowlage more then the average back yard machanic has.