2003 1500hd chevy silverado 6.0 liter. I had a

a fault with crankshaft position sensor will cause a no injector pulse on your 2006 chevy silverado 2500HD with the 6.0 Liter engine. have you checked your diagnostic trouble codes

Leaking intake manifold (vacuum )

po202=injector no 2 . po204= injector no 4. po206= injector no 6
po300=multiple misfire
hope it help

P0300 is multiple cylinder misfire, meaning a engine miss is detected on more then 1 cylinder, I would have the codes scanned at auto part store to know for sure which cylinders are actually missing, if there are 2 cylinders that are missing and they are side by side, such as cyl. 1,3. Or 3,5. If so its possible u have a blown head gasket blowing in between the 2 cylinders.. 1st double check that your wires are installed correctly, the coil packs have numbers on them to assure proper location.. Note the rear head has cylinder 1 3 and 5. Some people get that confused.. Providing you have a 3.3, 3.8 or 3.1 liter engine.

what code is check engine lite giving

check the feul pressure regulator disconent the vacuum hose while engine is running and see if there is any fuel comming from the port on the regulator if there is replace the regulator

You didn't mention the engine, so here are all options...

4.3 liter V-6 VIN "W" With Enhanced Ignition System


1996 Chevrolet C 1500 P/U 2WD
5.0 liter V-8 VIN "M OR
1996 Chevrolet C 1500 P/U 2WD
5.7 liter V-8 VIN "R "

Yes they could a PO300 is a generic misfire code. PO301 would be cylinder number 1 so on and so forth. check the resistance of your plug wires they should be approx. 7000 ohms per foot. it could also be a coil over plug. primary resistance of the cops should be 1-3 ohms. but since this is a misfire it would be your secondary. which should be between 20000-30000 ohms. hope I helped you out. Happy Motoring!

third back pass side the coil is probably bad if you have a miss code common problem

you have to read out the codes. po300 is misfire detected. maybe a coil or injector. could also be intake leak