Is this the networked Star TSP or the USB version? If it's networked you may want to make sure that you're still connected to the network by printing out a test receipt (power the printer off, hold the feed button down while it's off and continue holding the feed button after turning the printer back on until it prints a test receipt - the second receipt will give IP configuration information).
If you're not receiving a valid IP address you may be having network issues - you might consider assigning the printer (you might need to power cycle your router and printer to get initially connected again in order to do this).
You can also try resetting the printer to its default configuration - you can find instructions here:
Star TSP100Lan Network Troubleshooting Unable to Detect the Printer within...
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