I have a 65 watt marshall valvestate, it makes this random loud clug!clug! sound...what could cause this??

SOURCE: my marshall valvestate 100w combo makes a high

One of the tubes COULD be microphonic.

Take back off and use a pencil to lightly tap each tube to see if one causes noise.

SOURCE: marshall valvestate 8080 1. when i turn the buttons they make a cracking sound 2.when i play on it the sound becomes very quiet

As an electronics tech for 40 years I have spent half of those years reparing the damage done to electronic equipment by WD40. It is a great product when used in the correct situation. When it comes to cleaning controls in amplifiers etc the correct procedure is to apply a contact cleaner to flush out any dirt then apply a contact lubricant. WD40 contains minute graphite particles as well as corrosive chemicals. Between the two they swiftly render the controls to the bin.
WD40 great for unlocking rusty screws etc but never use it in electronic gear.

SOURCE: its a marshal 8080 valvestate 80 v and it buzzes

Buzzing could be normal for this amp, especially if you have the gain cranked way up (or the volume way up) see if the buzz goes away when you turn the gain/volume down. If not, there is a problem that needs to be properly diagnosed by the amp tech at your local music store. The crackling is also unfortunately rather normal for an amp that's a little older. Oxidation builds up inside the knobs and makes that noise as you turn them. If it only happens when you change settings I wouldn't worry about it, but if it gets bad, a tech guy can clean it out for you.