Camera wont acknowledge computer or visa versa

Did you mean that your computer does not detect your camera when you connect to it? How do you connect your camera to the computer? by usb port? try the following, one by one:

1. check by connecting to a different USB port in your computer.
2. check by using a different USB cable.
3. check by connecting to a different computer.
4. if your camera came with a disc - install it in your computer and then try again.

which operating system are you using - XP? Vista? Win7?