You may have blown a fuse in the amplifier. Refer to Appendix A: Service Info in this guide
http://www.mackie.com/products/mr5/pdf/mr5_om.pdf under No Power section, and if the fuse it not blown, try some of the solutions under No Sound. Hope this helps!
Need more info to solve your problem. Do they power on? What is your setup? What cables are you using to connect the monitors (TRS, RCA, XLR)? Did you adjust the input level?
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